Causes of Cellulite Cellulite is the result of two main factors. First is the development of more fat cells brought on by a variety of reasons, such as hormonal imbalances, poor diet and exercise habits, toxin build-up, or pregnancy. These fat deposits push against the fascia that connects the skin to the underlying muscle and create the appearance of dimpled or lumpy skin that is typical of cellulite. The second factor is characterized by an inefficient lymphatic drainage sy